Spravato® (Esketamine) Treatment Center in Longview, TX

Advanced care for treatment-resistant depression and acute suicidal thoughts

Specialized Spravato® treatment in a safe, supervised setting

C‑Trilogy Outreach is a certified Spravato® treatment center, offering FDA-approved esketamine nasal spray therapy in a safe, supervised setting. Treatment with Spravato® is designed for adults facing treatment-resistant depression (TRD) or major depressive disorder (MDD) with acute suicidal ideation.

Why choose Spravato® at C‑Trilogy Outreach?

  • We meet all Risk Evaluation and Mitigation Strategy standards administering Spravato® only in-clinic with at least two hours of post-dose observation for safety.

  • Our Psychiatric Mental Health Nurse Practitioners and other medical providers are trained to deliver and monitor Spravato®, ensuring personalized care.

  • Many patients experience symptom relief within hours or days — unlike traditional antidepressants that can take weeks.

  • Your Spravato® treatment is coordinated with therapy, medication management, and wellness services already offered at C‑Trilogy.

Who is eligible?

Spravato® is available for adults (18+) who:

  • Have tried at least two antidepressant treatments without sufficient improvement, or

  • Are experiencing acute suicidal thoughts alongside their depression

Treatment process at C-Trilogy

1. Initial evaluation

Comprehensive psychiatric assessment to determine suitability.

2. Treatment plan setup

Typically includes twice-weekly sessions (4–6 weeks), with possible transition to maintenance dosing.

3. In-clinic administration

Nasal spray given under supervision; patients observed for a minimum of 2 hours post-dose.

4. Ongoing monitoring

As a Schedule III controlled substance, Spravato® carries certain risks—such as dissociation, sedation and increases in blood pressure — that require onsite monitoring and adherence to the REMS program.

5. Support & coordination

Integration with your mental health professional and care team for comprehensive support.

Get Started With Spravato® at C‑Trilogy

To find out if Spravato® is right for you, schedule an assessment today. Our team is ready to guide you through every step to find the treatment that fits your individual journey.